Sodium thiosulfate, commonly known as sodium thiosulphate, is a medicine that is used to treat cyanide poisoning, pityriasis versicolor, and cisplatin side effects. It is frequently used after the drug sodium nitrite for cyanide poisoning and is usually only prescribed in severe situations.

Sodium Thiosulfate is a toxin with a modest toxicity level. Large dosages may produce nausea, vomiting, abdominal cramps, diarrhoea, metabolic acidosis, and hypernatremia, as well as gastrointestinal discomfort.